Probing ON and OFF Retinal Pathways in Glaucoma Using Electroretinography
نویسندگان
چکیده
منابع مشابه
Noninvasive assessment of retinal function in rats using multifocal electroretinography.
PURPOSE To assess the applicability of multifocal electroretinograms (mfERGs) for evaluation of function in this small-eyed animal with a rod-dominant retina that is often used to model retinal diseases. METHODS Noninvasive monocular mfERGs were recorded in anesthetized albino (Sprague-Dawley) and pigmented (Long Evans) rats. Achromatic stimuli subtending a 49 degrees by 53 degrees field cons...
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PURPOSE To explore retinal ganglion cell (RGC) dysfunction in glaucoma suspects and patients with early primary open angle glaucoma (POAG) using pattern electroretinography (PERG). METHODS Twenty glaucoma suspects (glaucomatous optic disc appearance), 15 early POAG (based on abnormal discs and abnormal visual fields) and 16 normal controls were enrolled. Transient PERG was recorded in respons...
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TRAUMATIC retinal detachment may or may not be associated with hypotony. In some cases iridocyclitis precedes the detachment, which is then termed secondary (Duke-Elder, 1940), and in these circumstances there is frequently a marked hypotension. Rarely, however, the reverse may occur and a detachment may be associated with a secondary iridocycitis giving rise to secondary glaucoma. This is thou...
متن کاملSelective glycine receptor α2 subunit control of crossover inhibition between the on and off retinal pathways.
In the retina, the receptive fields (RFs) of almost all ganglion cells (GCs) are comprised of an excitatory center and a suppressive surround. The RF center arises from local excitatory bipolar cell (BC) inputs and the surround from lateral inhibitory inputs. Selective antagonists have been used to define the roles of GABA(A) and GABA(C) receptor-mediated input in RF organization. In contrast, ...
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Detection of glaucoma eye disease is still a challenging task for computer-aided diagnostics (CADx) systems. During eye screening process, the ophthalmologists measures the glaucoma by structure changes in optic disc (OD), loss of nerve fibres (LNF) and atrophy of the peripapillary region (APR). In retinal images, the automated CADx systems are developed to assess this eye disease through segme...
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ژورنال
عنوان ژورنال: Translational Vision Science & Technology
سال: 2020
ISSN: 2164-2591
DOI: 10.1167/tvst.9.11.14